We provide professional support in Genetic Test.
As is known, cancer is a genetic disease, that is, cell
change occurs with gene change, and then the cells first spread locally and
then to the blood and lymph vessels. This gene change is sometimes
congenital (Hereditary cancers) and sometimes later with the effect of risk
factors (Acquired-environmental). Genetic changes, which were previously
small in number and amount, are increasing over time. This creates new
types of cell groups within the cancer mass, and gives them drug
resistance-sensitivity or organ metastasis capability. The characteristics
of genetic changes in the last 20 years can be easily understood with
In the first decade of 2000, the sequence analysis of all genes was made with
the human genome project. Parallel to this, the type and functions of
genetic changes in the cancer mass or cells are gradually better understood and
widely entered into patient practice for diagnosis and treatment.
In our country, these technologies are rapidly received from developed western
countries. The name and importance of the genetic tests performed in our
oncology unit are listed below.
BRCA1 mutation screening test: In identifying familial
risk in patients with young age and strong family history of breast ca.
K-ras mutation screening test: In deciding whether to
apply anti-EGFR treatment in colon cancer and in predicting whether EGFR-TKI
targeted treatment drugs will benefit from lung cancer.
EGFR gene mutation screening test: In deciding the
selection of a more effective targeted therapy than chemotherapy in lung